Biochemistry and molecular biology

An excess of osteoclasts is the culprit behind brittle bones in Hajdu-Cheney syndrome.

The stability of a virus' hemagglutinin protein affects its potential to cause pandemics.

Citrullinated tenascin-C may offer the ability to detect incipient rheumatoid arthritis in a subset of patients as much as 16 years before the onset of disease

Follicular lymphoma is currently viewed as a single disease entity – but will recent pathologic findings redefine our perspective?

Voted Number One on The Pathologist Power List, Manuel Sobrinho-Simões, talks profession, politics, education, innovation, and the ups and the downs of a career that has inspired generations of pathologists.

It’s often difficult to target pancreatic cancer cells while sparing healthy tissue – but a new therapy concept not only makes this possible, but also enhances the potential effectiveness of adjuvant treatments

When genetics yielded unsatisfactory answers about pancreatic cancer’s persistent survival, researchers looked beyond the genome – and found telling epigenetic changes

Screening for pancreatic cysts can help with early detection and treatment – but how can we tell which lesions are benign and which may progress to cancer?

Pancreatic cancer is often treated as a homogeneous disease, but new research reveals distinct subtypes of tumor and stromal gene expression

Pancreatic cancer is a challenge to stage because there’s no good molecular imaging method – but three new antibody conjugates may change that