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Companion diagnostics

Inside the Lab Companion diagnostics

Fluid Evidence

Liquid biopsy can help us appropriately treat patients with anti-PD-L1 immunotherapies, and ddPCR enables ongoing monitoring and adjustment of treatment

Subspecialties Biochemistry and molecular biology

A Boost for Cervical Cancer Screening

An efficient alternative to pap-HPV tests could lie with ddPCR and a ccfDNA assay

Inside the Lab Genetics and epigenetics

A Guiding Light for Molecular Testing

| Antonia R. Sepulveda

New collaborative guidelines for molecular biomarker testing in colorectal cancer

Diagnostics Regulation and standards

Seeking the Killer App

| David Rimm

An examination of domain-specific companion diagnostic testing

Outside the Lab Profession

Inside Industry

| Bharathi Vennapusa

An industry pathologist’s perspective on developing a companion diagnostic

Outside the Lab Quality assurance and quality control

A Blueprint for the Future

| Henrik Winther and Hans Christian Pedersen

Industry and regulators collaborate to harmonize or consolidate PD-1/PDL-1 assays

Outside the Lab Profession

Liquid Biopsy and NGS: Teaming Up to Take Cancer Apart

| Nicola Normanno, Jose Machado

How liquid biopsy and next-generation sequencing fit into the pathology lab of the future

Diagnostics Profession

Marker of Excellence

| Fedra Pavlou

Anthony Whetton, Director of the Stoller Biomarker Discovery Centre, Manchester, UK

Outside the Lab Liquid biopsy

Liquid License

| Michael Schubert

FDA issues first-ever approval for liquid biopsy companion diagnostic

Inside the Lab Profession

Empowering Pathologists

| Ralf Huss

Digital pathology and tissue image analysis tools are essential to developing companion diagnostics and enabling pathologists to support clinical decisions, but there is still work to be done…


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