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App Notes

Results 1–10 of 72

NGS technology: Trends and clinical applications

| Contributed by GE

White paper discussing DNA sequencing using next-generation technologies in e.g. reproductive health, oncology, and Mendelian diseases.

Comparison of cfDNA Reference Material Prepared using Enzymatic Fragmentation or Sonication for the Validation of Liquid Biopsy Assays

| Contributed by Horizon

Liquid biopsies hold great promise to revolutionize the field of clinical oncology testing.

Identifying Collagen Fiber Types I and III Stained with Picrosirius Red Using the BX53 Microscope Equipped with Olympus’ High Luminosity and High Color Rendering LED

| Contributed by Olympus Europa

To observe collagen fibers, samples can be stained with Masson trichrome (MT), Elastica van Gieson (EVG), or Elastica Masson (E-M).

The Analysis of FFPE Samples by Next-Generation Sequencing (NGS) of Key Genes for Research into Breast and Ovarian Cancer

| Contributed by Oxford Gene Technology

One of the challenges in cancer research is the high level of genetic complexity and tumour heterogeneity.

Assessment of the performance of a hybridisation-based NGS enrichment panel with as little as 10 ng of severely formalin-compromised DNA

| Contributed by Oxford Gene Technology

DNA reference standards with different levels of formalin-induced damage were hybridised and sequenced with a SureSeqTM custom NGS panel.

Selecting the best NGS enrichment assay for your needs

| Contributed by Oxford Gene Technology

Next generation sequencing (NGS) is now in routine use for a broad range of research and clinical applications.

What’s wrong with my FFPE FISH?

| Contributed by Oxford Gene Technology

Over 27 years, OGT has built up an intimate knowledge of all stages of the FISH processing workflow.

Reducing your FISH probe validation burden: Cytocell Aquarius® AML and MDS FDA-cleared FISH probes

| Contributed by Oxford Gene Technology

This application note describes the detailed clinical and analytical studies carried out to meet the performance required to achieve FDA clearance.

SureSeq™ FFPE DNA Repair Mix* and hybridisation-based enrichment provide superior variant detection in next-generation sequencing even from 10 ng of severely formalin compromised DNA

| Contributed by Oxford Gene Technology

With advances in next-generation sequencing (NGS) technology, genetic information can be extracted from an increasingly diverse range of samples.

What to Consider When Choosing a Microscope Camera

| Contributed by Olympus Europa

Thanks to recent advances in technology, there are many interesting microscopy-dedicated cameras available on the market.

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