Antibody Choice Alters Breast Cancer Subtyping
October 10, 2025
By Kathryn Wighton
Researchers compared MIB1 and SP6 antibodies for Ki-67 assessment in breast carcinoma.
1 min read
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Molecular Pathology
Research, trends, news, and views
Spatial Proteomics in Cancer Risk Predictions
October 7, 2025
By Helen Bristow
AI-powered test enhances progression risk assessment in esophageal cancer
5 min read
p63 Immunohistochemistry May Skew Breast Cancer Diagnosis
October 3, 2025
Researchers show that p63 expression occurs in most high-grade invasive breast carcinomas.
2 min read
Surrogates with Substance: Decoding Soft Tissue Tumors
September 30, 2025
By Jessica Allerton
Following a new CAP review, Jason L. Hornick discusses the strengths – and limitations – of IHC as a stand-in for molecular testing
4 min read
Biomarker in Fibrotic Lung Disorders Explored in Study
September 30, 2025
SPARC, an extracellular matrix protein, is identified as prognostic marker in interstitial lung diseases, including unclassifiable cases
2 min read
![Biomarker in Fibrotic Lung Disorders Explored in Study[]'](https://res.cloudinary.com/broadcastmed/image/fetch/q_auto,c_fill,g_faces:center,f_auto/https://texere-v2.useast01.umbraco.io//media/21zbn4bx/1025-101-ai-news-biomarker-in-fibrotic-lung-disorders-explored-in-study_teaser.jpg)
New Rules Aim to Standardize HRD Testing in Cancer Labs
September 25, 2025
Consensus recommendations standardize homologous recombination deficiency testing for clinical molecular laboratories
2 min read
Metaplastic Breast Cancer: Mouse Model Points to Therapeutic Target
September 24, 2025
By Kathryn Wighton
Keratin 15–driven mouse model shows diverse tumor types and suggests that tumors with PI3K mutations may respond to the drug alpelisib.
2 min read
Enable Comprehensive Genomic Profiling with Product Updates on TruSight™ Oncology 500 v2
September 23, 2025
TruSight™ Oncology 500 v2 (TSO500v2) is an updated next-generation sequencing (NGS) assay designed to enable laboratories with in-house comprehensive genomic profiling (CGP) from formalin-fixed, paraffin-embedded (FFPE) tissue samples...
12:00 pm - 1:00 pm GMT-4 min read
Wilson Disease Steatosis: Diet Versus Copper
September 22, 2025
By Kathryn Wighton
Copper, ceruloplasmin, and fibrosis pathways mapped in patients and knockout mice reveal diagnostic insights for Wilson disease
2 min read
Is it Time to Modernize Clinical Trials?
September 18, 2025
By Helen Bristow
With millions of contextualized patient data records now available across oncology, clinical development needs to evolve for the precision medicine era, says Gen Li
6 min read
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