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Precision medicine

Diagnostics Biochemistry and molecular biology

A Disease With Many Faces

| David R. Hout

Triple-negative breast cancer is not a single entity, and understanding each patient’s molecular subtype can influence treatment and outcomes

Inside the Lab Precision medicine

Next-Generation Sequencing: Will It Really Replace Single-Gene Tests in Pathology Labs?

| Sponsored by Thermo Fisher Scientific

The move to in-house next-generation sequencing has resulted in time and tissue savings, and improved collaboration across cancer care specialties

Subspecialties Clinical care

An Inside Look at the CNS

| Danielle Fortuna, Mark Curtis

Neurological disorders can be invasive and time-consuming to diagnose, but profiling cytokines in the cerebrospinal fluid can lessen that burden

Diagnostics Digital and computational pathology

Biosensors for the Future

| Luke Turner

From a new material for lung cancer diagnosis to real-time robotics for monitoring reproductive hormones, discover our latest bite-sized breakthroughs

Inside the Lab Clinical care

Positive Steps to Tackle Triple-Negative Breast Cancer

| Jane Armes

Jane Armes discusses the value of molecular subtyping and targeted therapies in triple-negative breast cancer

Inside the Lab Biochemistry and molecular biology

A Fluid Future

| Luke Turner

Liquid biopsy has shown promise as a rapid, minimally invasive way to profile tumors – but are commercially available tests accurate and consistent?

Subspecialties Genetics and epigenetics

Putting a Bug in Your Ear

| Michael Schubert

Variants in the FUT2 gene may increase susceptibility to otitis media by altering the microbiome of the middle ear

Diagnostics Liquid biopsy

A Diagnostic to Drool Over?

| Luke Turner

The use of saliva as a diagnostic fluid seems an attractive option – especially now that research reveals circulating tumor DNA in the fluid

Diagnostics Genetics and epigenetics

Scrutinizing Breast Cancer

| Michael Schubert

The FLEX breast cancer registry intends to collect complete information on 10,000 patients over the course of 10 years

Diagnostics Biochemistry and molecular biology

Treat or Surveil

| George Vasmatzis and John Cheville

Newly discovered genetic alterations could indicate whether treatment or active surveillance is the best option for low-risk prostate cancer patients

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