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Precision medicine

Inside the Lab Precision medicine

All the RAGE

| Luke Turner

A new genomic barcode tracker could help spot the rare immune cells that are most effective against cancer

Inside the Lab Biochemistry and molecular biology

Super Method Seeks Cancer's Kryptonite

| Jonathan James

The combination of genome-scale CRISPR experiments and powerful computational approaches has created a Cancer Dependency Map

Inside the Lab Regulation and standards

Wasting the Gift of Life?

| Sumit Mohan

Kidney discard rates are higher than ever – but the procurement biopsies that often rule out their use are unreliable and need to be standardized

Inside the Lab Genetics and epigenetics

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

Diagnostics Precision medicine

Time, Money, and Tissue

| Jason Ramos

Simultaneous multiplex immunohistochemistry can provide efficient testing of multiple targets when diagnosing and selecting treatment for cancer

Diagnostics Companion diagnostics

Improving Patient Outcomes

| Eslie Dennis, Eric Walk, Ken Bloom, Mark Kockx

A response to David Rimm’s letter that supports the role of PD-L1 testing in improving outcomes for cancer patients.

Diagnostics Companion diagnostics

Welcome to Our Kitchen

| David L. Rimm

David Rimm challenges the sensitivity and reproducibility of a new assay for PD-L1 detection.

Diagnostics Liquid biopsy

Fine-Tuning Immunotherapy

| George Karlin-Neumann

Techniques like droplet digital PCR technology can assist with early monitoring of cancer immunotherapy to ensure the right treatment for each patient

Outside the Lab Profession

The Spice of Life

| Luke Turner

Genomic research has a diversity problem that could restrict the future effectiveness of precision medicine for minority groups

Inside the Lab Precision medicine

PREDICTive Power

| Jonathan James

Prostate cancer prognosis presents a challenge – but a new algorithmic tool may help personalize predictions

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