Biochemistry and molecular biology

A triple-transgenic mouse model allows researchers to trace the lineage of EMT tumor cells, and reveals the transition’s surprising lack of significance in metastasis

Recent studies reveal that the organizational protein complexes in gut microvilli closely resemble those of ear stereocilia – so what does this mean for genetic disorders of either?

Two recent studies on EMT may revise the field’s understanding of the process – but it’s important to keep in mind both the breakthroughs and the limitations of the work

Long thought to be a key component of the metastatic process, researchers are now questioning long-held beliefs of the role of epithelial-to-mesenchymal transition

A blood test for circulating tumor DNA can reveal what’s going on below the surface of malignant melanoma

Molecular testing is changing the face of healthcare. But how far should it go?

Hirschsprung disease (HSCR) is a congenital form of megacolon that occurs when the ganglion cells of the digestive tract fail to develop, impairing or eliminating function.

A unique odor signature in the urine of Alzheimer’s mouse models may one day lead to simple tests for the disease

Urine cathepsin C testing may offer quicker, cheaper Papillon-Lefèvre syndrome detection

Insulin resistance in the brain adds a new dimension to Alzheimer's disease understanding.