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Biochemistry and molecular biology

Diagnostics Oncology

An Epigenetic Epiphany

| Michael Schubert

When genetics yielded unsatisfactory answers about pancreatic cancer’s persistent survival, researchers looked beyond the genome – and found telling epigenetic changes

Outside the Lab Oncology

Friend or Foe?

| Anne Marie Lennon

Screening for pancreatic cysts can help with early detection and treatment – but how can we tell which lesions are benign and which may progress to cancer?

Diagnostics Oncology

Surprising Subtypes

| Michael Schubert

Pancreatic cancer is often treated as a homogeneous disease, but new research reveals distinct subtypes of tumor and stromal gene expression

Diagnostics Oncology

New Ab-ilities in Imaging

| Michael Schubert

Pancreatic cancer is a challenge to stage because there’s no good molecular imaging method – but three new antibody conjugates may change that

Diagnostics Oncology

Tapping a Rich Vein

| Christopher Chapman

Circulating tumor cells may hold information crucial for better pancreatic cancer diagnosis and treatment – but locating them needs special tactics

Diagnostics Oncology

A New Dimension in Biomarker Research

| Xia-Jun Ma

RNA in situ hybridization offers a new way to overcome the challenges of advancing RNA cancer biomarkers to the clinic

Diagnostics Profession

Plus Ça Change!

| Roisin McGuigan

We Sit Down With Michael Wells, Past President of the European Society of Pathology.

Diagnostics Genetics and epigenetics

The Dark Virome

| Roisin McGuigan

Over 90 percent of the human cutaneous virome is made up of unclassifiable “dark matter”

Diagnostics Hematology

This Sporting Life

| Giuseppe Banfi

Physical activity is an important preanalytical variable in blood analysis and here’s why.

Diagnostics Microbiology and immunology

Time for a Culture Change

| Eshwar Mahenthiralingam

Molecular techniques can offer rapid, accurate diagnosis of lung infections in cystic fibrosis, but most labs feel the technologies are out of reach. What if there was an affordable alternative?

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