100 of the best, brightest, and most powerful advocates of pathology.
Celebrating 100 inspirational and influential professionals in laboratory medicine.
Niamh Buckley, Laura Feeney, James Beirne, and Paul Mullan
Markers such as DNA methylation, analyzed by liquid biopsy, may improve on ovarian cancer testing options like gold standard CA125
New biomarker sensing technology can detect miniscule concentrations of molecules in the blood to assist with patient monitoring
Epigenetics may combine with liquid biopsy to offer an effective way of detecting early-stage cancers and recurrences
With antimicrobial resistance an ever-increasing threat to modern medicine, a new breakthrough may rapidly identify drug-resistant microbe strains to ensure effective treatment
A new DNA test that can detect treatment-resistant mutations could prove crucial for patients with acute myeloid leukemia, providing an early indication that targeted therapeutic intervention is needed
A combination of magnetic particles that bind circulating tumor cells and a magnetic wire that samples them directly from the vein could lead to earlier diagnosis
The serum free light chain assay for myeloma may miss as many as one in four cases of lambda chain-associated disease, so additional testing is advised
Digital spatial profiling technology may enable researchers to identify biomarkers that indicate how patients with high-risk melanoma will respond to treatment
Measuring the levels of two brain proteins in the blood can yield insight into which TBI patients require CT scanning or surgery
For better diagnosis and monitoring of Alzheimer’s disease, as well as drug R&D, we need to move toward widespread use of MRI biomarker imaging, even if blood screening tests become a reality
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