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Omics

Inside the Lab Precision medicine

The Next Generation of Variant Profiling

| Anoop Grewal

In-depth analysis of next-generation sequencing can help personalize cancer treatment and drive the adoption of precision medicine

Diagnostics Genetics and epigenetics

Unraveling Complexity

| Michael Schubert

A new kind of deep learning model uses nonlinear information to draw new associations between genes and diseases

Diagnostics Genetics and epigenetics

A Pharmacogenomic Promise

| Michael Schubert

Pharmacogenomic testing can only improve patient care if it’s clinically validated, judiciously applied, and easily understood by healthcare providers

Diagnostics Genetics and epigenetics

Exploring the Epi-signature

| Luke Turner

New research shows that genome-wide testing of DNA methylation can diagnose previously unsolved cases of neurodevelopmental and congenital anomalies

Diagnostics Liquid biopsy

IAs – IDed

| Jonathan James

The transcriptome of circulating neutrophils may contain a signature that allows the early detection of intracranial aneurysms via blood test

Diagnostics Omics

A Microbial Map to Cancer

| Michael Schubert

A new study uses machine learning to perform meta-analysis of eight metagenomic studies linking gut microbial signatures with colorectal cancer.

Diagnostics Genetics and epigenetics

IEM Identification

| Jonathan James

Combining metabolomics and DNA sequencing could be the key to discovering new inborn errors of metabolism in children.

Outside the Lab Laboratory management

The Finding You Weren’t Looking For

| Tieneke B. M. Schaaij-Visser, Gerhard A. Zielhuis

Study participants can offer a valuable resource to researchers deciding which unsolicited findings to report and why.

Diagnostics Omics

Serving China’s Breast Cancer Community

| Franklin Libenson

Decentralized genomic testing in China will allow earlier breast cancer diagnosis and more personalized treatment decisions

Inside the Lab Liquid biopsy

CTCs in a Spin

| Luke Turner

A microfluidic device reveals new insights into the function of circulating tumor cells, providing vital information on how cancers metastasize.

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