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Liquid biopsy

Diagnostics

The Evolution of Epigenetic Biomarkers

| Niamh Buckley, Laura Feeney, James Beirne, and Paul Mullan

Markers such as DNA methylation, analyzed by liquid biopsy, may improve on ovarian cancer testing options like gold standard CA125

Diagnostics

Sensing the Tiniest Change

| Menno Prins

New biomarker sensing technology can detect miniscule concentrations of molecules in the blood to assist with patient monitoring

Diagnostics

Thinking Outside the (Genome) Box

| Jason Mellad

Epigenetics may combine with liquid biopsy to offer an effective way of detecting early-stage cancers and recurrences

Inside the Lab

One Drop at a Time

| Alexander Dobrovic and Cloud Paweletz

When seeking the greatest benefit from liquid biopsy, droplet digital PCR can help by offering speed, sensitivity, and absolute quantitation

Inside the Lab

Gone Fishing

A combination of magnetic particles that bind circulating tumor cells and a magnetic wire that samples them directly from the vein could lead to earlier diagnosis

Outside the Lab

Fighting Resistance in Bloodstream Infections

| Luke Turner

When bacteria become resistant to the last line of defense, rapid detection and treatment is more important than ever. A new assay can help with treatment selection for carbapenem-resistant infections

Inside the Lab

Fluid Evidence

Liquid biopsy can help us appropriately treat patients with anti-PD-L1 immunotherapies, and ddPCR enables ongoing monitoring and adjustment of treatment

Outside the Lab

The Gentle Fetal Genome

| William Aryitey

Inertial microfluidics for fetal screening

Outside the Lab

Faster Fibrosis Diagnosis

| William Aryitey

An immunosensing technique that detects liver fibrosis in 45 minutes

Subspecialties

A Boost for Cervical Cancer Screening

An efficient alternative to pap-HPV tests could lie with ddPCR and a ccfDNA assay


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