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Liquid biopsy

Inside the Lab Technology and innovation

Solving the Big Problems

| Luke Turner

We speak to bioengineer Stephen Quake to learn about the noninvasive prenatal tests that have saved thousands of pregnant women’s lives

Diagnostics Liquid biopsy

Game of Exosomes

| Luke Turner

A lab-on-a-chip device that can detect exosomes from tumors in the blood could revolutionize early cancer diagnosis

Diagnostics Hematology

Improving Our Early Warning System for AML

| Amanda Winters

The gold standard for monitoring acute myeloid leukemia relapse after bone marrow transplant is chimerism testing – but is it sensitive enough?

Inside the Lab Biochemistry and molecular biology

A Fluid Future

| Luke Turner

Liquid biopsy has shown promise as a rapid, minimally invasive way to profile tumors – but are commercially available tests accurate and consistent?

Diagnostics Liquid biopsy

A Diagnostic to Drool Over?

| Luke Turner

The use of saliva as a diagnostic fluid seems an attractive option – especially now that research reveals circulating tumor DNA in the fluid

Inside the Lab Liquid biopsy

Building a Better Biopsy

| Lisa M. Wright

To harness liquid biopsy’s many advantages, it’s vital to ensure appropriate testing – and cfDNA synthetic plasma reference standards can help

Diagnostics Genetics and epigenetics

The Evolution of Epigenetic Biomarkers

| Niamh Buckley, Laura Feeney, James Beirne, and Paul Mullan

Markers such as DNA methylation, analyzed by liquid biopsy, may improve on ovarian cancer testing options like gold standard CA125

Diagnostics Analytical science

Sensing the Tiniest Change

| Menno Prins

New biomarker sensing technology can detect miniscule concentrations of molecules in the blood to assist with patient monitoring

Diagnostics Genetics and epigenetics

Thinking Outside the (Genome) Box

| Jason Mellad

Epigenetics may combine with liquid biopsy to offer an effective way of detecting early-stage cancers and recurrences

Inside the Lab Biochemistry and molecular biology

One Drop at a Time

| Alexander Dobrovic and Cloud Paweletz

When seeking the greatest benefit from liquid biopsy, droplet digital PCR can help by offering speed, sensitivity, and absolute quantitation

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