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Biochemistry and molecular biology

Diagnostics Microscopy and imaging

Virus Vision

| Michael Schubert

A new method uses fluorescent proteins to highlight virus-infected cells and shows which proteins are affected

Subspecialties Genetics and epigenetics

Disrupting Cytogenetics in the Clinic

| George Vasmatzis

To select the right treatment for each cancer patient, we need fast, accurate and cost effective ways to characterize tumors. Now, with newly developed algorithms and protocols, mate pair sequencing could well be the tool we’ve been seeking

Diagnostics Clinical care

Waging War on Pathogens

| Nancy Hanson

Molecular diagnostics are welcome reinforcements in the raging battle against institutional infection and antibiotic resistance

Diagnostics Genetics and epigenetics

Biomarker to Predict Breast Cancer

| Michael Schubert

Ki67 in healthy breast tissue may indicate increased risk of developing the disease

Diagnostics Oncology

Research Timeline

An overview of epithelio-mesenchymal transition

Diagnostics Oncology

The PDAC Key

| Michael Schubert

Pancreatic cancer cells don’t seem to rely on EMT for metastasis – but it plays a key role in their ability to resist our best chemotherapy options

Diagnostics Oncology

Tracking the Transition

| Dingcheng Gao

A triple-transgenic mouse model allows researchers to trace the lineage of EMT tumor cells, and reveals the transition’s surprising lack of significance in metastasis

Diagnostics Histology

Listen to your Gut

| Jianchao Li, Scott Crawley

Recent studies reveal that the organizational protein complexes in gut microvilli closely resemble those of ear stereocilia – so what does this mean for genetic disorders of either?

Diagnostics Oncology

Proceed With Caution

| Shyamala Maheswaran

Two recent studies on EMT may revise the field’s understanding of the process – but it’s important to keep in mind both the breakthroughs and the limitations of the work

Diagnostics Oncology

Cells on the (Invasion) Front Lines

| Michael Schubert

Long thought to be a key component of the metastatic process, researchers are now questioning long-held beliefs of the role of epithelial-to-mesenchymal transition

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