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Oncology

Subspecialties Biochemistry and molecular biology

A Longer Life With Liver Cancer

| Luke Turner

Targeting a pathway that promotes cancer immune evasion could prolong immunotherapy and reduce its side effects for liver cancer patients

Inside the Lab Biochemistry and molecular biology

Super Method Seeks Cancer's Kryptonite

| Jonathan James

The combination of genome-scale CRISPR experiments and powerful computational approaches has created a Cancer Dependency Map

Outside the Lab Guidelines and recommendations

The Blue Books Are Back!

| Luke Turner

The WHO’s Classification of Tumors series is entering its fifth edition – and many accessibility improvements make the latest Blue Books the best yet

Diagnostics Precision medicine

Time, Money, and Tissue

| Jason Ramos

Simultaneous multiplex immunohistochemistry can provide efficient testing of multiple targets when diagnosing and selecting treatment for cancer

Diagnostics Microscopy and imaging

Taking Aim at a Moving Target

| Michael Schubert

A new imaging technique provides detailed views of tumor cells, allowing researchers to visualize the transition from precancerous to cancerous

Subspecialties Microbiology and immunology

A Meaningful Microbiome

| Michael Schubert

The microbial diversity and species distribution of the cervix may help diagnosticians determine the patients at increased risk of cervical cancer.

Diagnostics Companion diagnostics

Improving Patient Outcomes

| Eslie Dennis, Eric Walk, Ken Bloom, Mark Kockx

A response to David Rimm’s letter that supports the role of PD-L1 testing in improving outcomes for cancer patients.

Diagnostics Companion diagnostics

Welcome to Our Kitchen

| David L. Rimm

David Rimm challenges the sensitivity and reproducibility of a new assay for PD-L1 detection.

Diagnostics Liquid biopsy

Fine-Tuning Immunotherapy

| George Karlin-Neumann

Techniques like droplet digital PCR technology can assist with early monitoring of cancer immunotherapy to ensure the right treatment for each patient

Diagnostics Omics

A Microbial Map to Cancer

| Michael Schubert

A new study uses machine learning to perform meta-analysis of eight metagenomic studies linking gut microbial signatures with colorectal cancer.

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