A Meaningful Microbiome
Cervical microbiota could help diagnosticians spot patients at high risk of cancer
Michael Schubert | | Quick Read
The gut microbiome is increasingly well known for its diagnostic potential and its effect on overall health. But just because it’s the most famous doesn’t mean it’s the only one; a new study has revealed the potential of the cervical microbiome as a biomarker of cervical cancer risk.
A transatlantic group of researchers from the University of Nebraska–Lincoln and Tanzania’s Ocean Road Cancer Institute conducted a study to investigate the relationship between human papillomavirus (HPV), human immunodeficiency virus (HIV), and cervical dysplasia (1). To that end, they collected cytobrush samples from the cervical lesions of 144 Tanzanian women and performed 16S rRNA gene deep sequencing to examine the microbiota present. The goal? To understand how the bacterial community differs between patients with different HIV status and cytology grade.
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