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Subspecialties Oncology

Optimizing Hematological Malignancy Insights: Leveraging Advanced Informatic Platforms for Structural Variant Analysis from Optical Genome Mapping Data.

sponsored by Bionano

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Optical genome mapping (OGM) represents an innovative approach for exploring the intricate landscape of the genome, offering unparalleled insights into its structural complexities. 

Dr. Susan Crocker leverages OGM at Kingston Health Sciences Centre to characterize the genomic integrity of samples indicative for acute myeloid leukemia (AML). The Variant Intelligence Applications™ (VIA) software is designed to streamline the visualization, interpretation and reporting of variants detected with OGM data for an elevated analysis of hematological malignancies.  

In this webinar, Dr. Susan Crocker will share her findings from several samples analyzed with OGM and VIA™ software, shedding light on how this innovative cytogenetic approach is revolutionizing her clinical research laboratory. Notably, VIA software stands out as the sole software solution to integrate the analysis of next-generation sequencing (NGS) and microarray data types. 

Bionano’s Director of Software Product Management, Daniel Saul, will present the ways in which VIA software facilitates a seamless workflow for genomic research by offering a centralized solution for robust integration, scalability, and efficiency. Such features are vital for fostering collaboration among scientists. 

The combination of OGM and VIA software offers a comprehensive and automated workflow for analyzing, interpreting, and reporting of structural variants (SVs) and copy number variations (CNVs) associated with hematological malignancies. 

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