All the RAGE
Will “Repertoire and Gene Expression by Sequencing” drive the personalization of cancer immunotherapy?
Luke Turner | | Quick Read
Although immunotherapy is a promising form of cancer therapy, not all patients respond well – and current methods to assess an individual’s immune cell behavior often fall short. Immune cells that recognize cancer are rare, making it difficult to identify those that will mount an effective response. But that’s exactly what Repertoire and Gene Expression by Sequencing (RAGE-Seq) – a new cellular barcode tracker – aims to do. Developed by scientists at the Garvan Institute of Medical Research, the new technology can spot the rare lymphocytes that are most reactive against cancer cells, all from within the patient’s own immune system (1).
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