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Inside the Lab Biochemistry and molecular biology, Genetics and epigenetics, Oncology, Precision medicine

Super Method Seeks Cancer's Kryptonite

Decades of toil have led to significant breakthroughs in cancer diagnosis and treatment (1) – and many genetic loci have been pinpointed as key players in tumor development. But the search for more personalized therapy continues. Here, the combination of genome-wide CRISPR and computational biology may prove to be a powerful tool.

Fiona Behan is a Senior Scientist at the Wellcome Sanger Institute in Cambridge. With significant experience in genome-wide CRISPR, she was keen to apply the technology to oncology. “Collaborating with Kosuke Yusa, who was one of the leaders in developing genome-scale CRISPR technology, and Mathew Garnett, who had expertise in high-scale cancer screening, provided us with a great starting point for our research (2),” says Behan.

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About the Author

Jonathan James

As an assistant editor for The Translational Scientist, I can combine two of my passions; translational science research and science communication. Having thrown myself into various editing and other science communication gigs whilst at University I came to realise the importance of good quality content that delivers in an exciting and engaging way.

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