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Screening and monitoring

Inside the Lab Clinical care

Biochip Breakthrough

| Luke Turner, Arjang Hassibi

With antimicrobial resistance an ever-increasing threat to modern medicine, a new breakthrough may rapidly identify drug-resistant microbe strains to ensure effective treatment

Outside the Lab Biochemistry and molecular biology

Pre-Empting Relapse

| Luke Turner

A new DNA test that can detect treatment-resistant mutations could prove crucial for patients with acute myeloid leukemia, providing an early indication that targeted therapeutic intervention is needed

Inside the Lab Clinical care

Gone Fishing

A combination of magnetic particles that bind circulating tumor cells and a magnetic wire that samples them directly from the vein could lead to earlier diagnosis

Subspecialties Biochemistry and molecular biology

An Untrustworthy Myeloma Assay?

The serum free light chain assay for myeloma may miss as many as one in four cases of lambda chain-associated disease, so additional testing is advised

Inside the Lab Clinical care

Characterizing Cancer

| Luke Turner

Digital spatial profiling technology may enable researchers to identify biomarkers that indicate how patients with high-risk melanoma will respond to treatment

Inside the Lab Clinical care

A Biomarker for Brain Injury

Measuring the levels of two brain proteins in the blood can yield insight into which TBI patients require CT scanning or surgery

Outside the Lab Clinical care

Better Biomarkers for AD R&D

| Carlo Medici

For better diagnosis and monitoring of Alzheimer’s disease, as well as drug R&D, we need to move toward widespread use of MRI biomarker imaging, even if blood screening tests become a reality

Inside the Lab Analytical science

Coming Soon: Third-Wave Diagnostics

| Jason Heikenfeld

The need for continuous and contextual biochemical data is clearer than ever, and enabling technology may be just around the corner

Outside the Lab Bioinformatics

The Economics of Personalized Medicine

| Ilan Danieli

Broad NGS panels work well for cancer screening, but for monitoring, we need tools that are less expensive and more targeted

Outside the Lab Analytical science

Quick Hits

| William Aryitey

A roundup of interesting stories surrounding pathology

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