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Omics

Outside the Lab Oncology

A “Model” Career

| Keith Cheng

Curiosity’s road to pathology, zebrafish genetics, genomics and imaging

Diagnostics Genetics and epigenetics

A Personalized Reality

| Matthew Smith , George Burghel

Next generation sequencing holds much promise for personalized cancer diagnosis, treatment and management, but how is this being realized and what does the future hold?

Outside the Lab Genetics and epigenetics

Assemble the MinIONs

| Roisin McGuigan

A pocket-sized DNA sequencer powered by a USB connection could bring disease differentiation capabilities to remote locations

Subspecialties Genetics and epigenetics

Cancer’s Common Core

| Michael Schubert

Genetic flaws shared by all metastases of a single prostate cancer may be the key to personalized treatment.

Inside the Lab Regulation and standards

Clamping Down on Mistaken Identity

| Fedra Pavlou

Mislabeling and contamination of cell lines in labs are well-known issues, but often nothing is done about them; journal publishers are getting tough

Diagnostics Oncology

Buying the Hype

| Michael Schubert

As consumer genetic testing becomes cheaper and easier to access, medical professionals worry that unregulated Internet marketing may steer patients in the wrong direction

Inside the Lab Oncology

Tumor Only Sequencing Could Be Misleading

| Michael Schubert

Many hospitals sequence patients’ tumor genomes to personalize their treatment – but without sequencing normal tissue, this can harm rather than heal.

Diagnostics Biochemistry and molecular biology

A new ERA for IVF?

| Roisin McGuigan

Molecular testing of an endometrial biopsy could help fertility specialists choose the perfect time for embryo implantation

Outside the Lab Genetics and epigenetics

At the Helm of the Biological Revolution

| Jan Hoeijmakers

Sitting Down With… Jan Hoeijmakers, Head of the Institute of Genetics, Erasmus University Medical Centre, Rotterdam, the Netherlands.

Diagnostics Biochemistry and molecular biology

Targeted Metabolomics

| Hannah Noel

Should tandem mass spectrometry be used in the screening of inborn errors of metabolism?

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