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Biochemistry and molecular biology

Subspecialties Biochemistry and molecular biology

Identifying Parkinson’s Inhibitors

| Luke Turner

An innovative approach aims to find the most effective inhibitors of α-synuclein protein aggregation, which is a leading cause of Parkinson’s disease

Subspecialties Biochemistry and molecular biology

Journey to the Center of the Cell

| Luke Turner

A 3D model allows scientists to view live human cells in an unprecedented way, using an algorithm to display the shape and location of its structures

Subspecialties Analytical science

A Lasting Legacy

| Mary J. Wirth

A story of war, famine, epigenetics, and how all three colluded to change the phenotype of a generation of babies – and beyond

Diagnostics Analytical science

Sensing the Tiniest Change

| Menno Prins

New biomarker sensing technology can detect miniscule concentrations of molecules in the blood to assist with patient monitoring

Outside the Lab Genetics and epigenetics

A Global Citizen

We sit down with Malak Abedalthagafi to talk about the biggest issues facing pathology and how she has adapted to working around the globe

Inside the Lab Clinical care

Biochip Breakthrough

| Luke Turner, Arjang Hassibi

With antimicrobial resistance an ever-increasing threat to modern medicine, a new breakthrough may rapidly identify drug-resistant microbe strains to ensure effective treatment

Inside the Lab Biochemistry and molecular biology

One Drop at a Time

| Alexander Dobrovic and Cloud Paweletz

When seeking the greatest benefit from liquid biopsy, droplet digital PCR can help by offering speed, sensitivity, and absolute quantitation

Outside the Lab Biochemistry and molecular biology

Pre-Empting Relapse

| Luke Turner

A new DNA test that can detect treatment-resistant mutations could prove crucial for patients with acute myeloid leukemia, providing an early indication that targeted therapeutic intervention is needed

Diagnostics Biochemistry and molecular biology

Muscling in on Malignant Hyperthermia

| Bradley Launikonis

This dangerous condition can cause sudden death during surgery – but until now, testing has been unreliable and often painful and invasive

Subspecialties Biochemistry and molecular biology

An Untrustworthy Myeloma Assay?

The serum free light chain assay for myeloma may miss as many as one in four cases of lambda chain-associated disease, so additional testing is advised

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