Biochemistry and molecular biology

Automated IHC staining has limited capacity for heat-induced epitope retrieval – but a move to hybrid power lifts that barrier.

A new laser technique uses vibrations to listen to the metabolic activity of cancer cells, shedding light (and sound) on intratumoral heterogeneity.

Triple-negative breast cancer is not a single entity, and understanding each patient’s molecular subtype can influence treatment and outcomes

Pancreatic cancer is associated with poor patient outcomes; could a new blood test improve screening accuracy for those at risk?

D-serine has shown potential as a biomarker for the prediction of kidney function and the detection of chronic kidney disease

Different glycosylation patterns in patients with idiopathic REM sleep behavior disorder could predict the future onset of neurodegenerative disease

A Jagged protein directly linked to cancer metastasis could be targeted to assess the aggressiveness of tumors and prevent their rapid spread

Liquid biopsy has shown promise as a rapid, minimally invasive way to profile tumors – but are commercially available tests accurate and consistent?

Newly discovered genetic alterations could indicate whether treatment or active surveillance is the best option for low-risk prostate cancer patients

For regions with limited infrastructure, a device that can diagnose Kaposi’s sarcoma without the need for a steady power supply could be invaluable