Jagged Little Pill (for Cancer)
How can we use JAG1 – a small protein involved in cancer metastasis – to assess the aggressiveness of tumors and prevent clustered cell migration?
Luke Turner | | Quick Read
In our quest to discover the elusive “magic bullet” for cancer treatment, tumor cell heterogeneity represents a major stumbling block. Now, though, a team that spans Rice and Duke Universities has gained further insights into JAG1 – a small protein that drives metastasis by allowing cancer cells to migrate in multicellular clusters. Lead author Federico Bocci of Rice University is hopeful that the protein, which sheds new light on tumor aggressiveness, could be an important target for therapeutic intervention.
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