Cookies

Like most websites The Pathologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Subspecialties Biochemistry and molecular biology, Digital and computational pathology, Bioinformatics, Microscopy and imaging, Technology and innovation

Journey to the Center of the Cell

Would you like to see the intricate, complex structures inside a living human cell? Until recently, this would have been unheard-of. Now, the Allen Institute for Cell Science has developed a comprehensive three-dimensional model of a live human cell that allows researchers to dig into our bodies’ innermost secrets. The probabilistic model can accurately predict the shapes and locations of structures within a cell, a novel ability that the researchers hope will enhance our knowledge of cellular processes and facilitate a better understanding of human disease. To find out more about the mechanics and potential significance of the model, we went straight to the source.

What inspired you to develop this model?

Fluorescence imaging is incredibly powerful in that it allows us to see specific structures, but limited in that it only allows us to see a few components of living cells at any given time. We needed to develop methods that allowed us to integrate both of these abilities. Neural networks were a natural starting point because they permit us to scale the integration of dozens of cellular components, each learned from thousands of images, relatively easily.

Read the full article now

Log in or register to read this article in full and gain access to The Pathologist’s entire content archive. It’s FREE and always will be!

Login if you already created an account

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine
Register

Or Login as a Guest or via Social Media

About the Author

Luke Turner

While completing my undergraduate degree in Biology, I soon discovered that my passion and strength was for writing about science rather than working in the lab. My master’s degree in Science Communication allowed me to develop my science writing skills and I was lucky enough to come to Texere Publishing straight from University. Here I am given the opportunity to write about cutting edge research and engage with leading scientists, while also being part of a fantastic team!

Register to The Pathologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine

Register