How do human cells become immortal? Despite the important implications for cancer development, the process is not well understood. Now, a research team based in the Berkeley Lab, US, have developed a new method to create and study immortal human mammary epithelial cells (IHMECs). It is already possible to do this but the oncogenic agents used to create the cells result in multiple genomic errors, meaning the cells are not accurate models of cancer etiology. The new method generates cells with normal, stable genomes, providing a more accurate model for studying the process in the same way it actually occurs in human cancers; while human cancer tissue may contain many genomic alterations, only a small number of these are thought to play a role in disease development.
Enjoy our FREE content!
Log in or register to read this article in full and gain access to The Pathologist’s entire content archive. It’s FREE and always will be!
If you don’t have an account you can:
REGISTER NOW – it’s FREE and always will be!
You will benefit from:
- Unlimited access to ALL articles including Application Notes
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Pathologist magazine
Or Login as a Guest or via Social Media
This will allow you to read this article but you will only have limited access to The Pathologist.Login as Guest Twitter LinkedIn Google+ Facebook