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Companion diagnostics

Diagnostics Companion diagnostics

Atezolizumab Assay Angst

| David Rimm

David Rimm continues the conversation about the best assay for atezolizumab after a recent response to his original article

Diagnostics Companion diagnostics

Which Assay for Atezolizumab?

| Emina Torlakovic, Allen M. Gown

Emina Torlakovic and Allen Gown share their disagreements with David Rimm’s comments about an FDA-approved PD-L1 assay for atezolizumab

Diagnostics Companion diagnostics

What Would Your Oncologist Think If…

| Roberto Salgado

Not every assay that trials well is practical for implementation in daily practice. How can we tell which ones are, and whose responsibility is it?

Diagnostics Companion diagnostics

Improving Patient Outcomes

| Eslie Dennis, Eric Walk, Ken Bloom, Mark Kockx

A response to David Rimm’s letter that supports the role of PD-L1 testing in improving outcomes for cancer patients.

Diagnostics Companion diagnostics

Welcome to Our Kitchen

| David L. Rimm

David Rimm challenges the sensitivity and reproducibility of a new assay for PD-L1 detection.

Inside the Lab Companion diagnostics

Fluid Evidence

Liquid biopsy can help us appropriately treat patients with anti-PD-L1 immunotherapies, and ddPCR enables ongoing monitoring and adjustment of treatment

Subspecialties Biochemistry and molecular biology

A Boost for Cervical Cancer Screening

| Liang Cao, Zhigang Kang

An efficient alternative to pap-HPV tests could lie with ddPCR and a ccfDNA assay

Inside the Lab Genetics and epigenetics

A Guiding Light for Molecular Testing

| Antonia R. Sepulveda

New collaborative guidelines for molecular biomarker testing in colorectal cancer

Diagnostics Regulation and standards

Seeking the Killer App

| David Rimm

An examination of domain-specific companion diagnostic testing

Outside the Lab Profession

Inside Industry

| Bharathi Vennapusa

An industry pathologist’s perspective on developing a companion diagnostic

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