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Oncology

Outside the Lab Oncology

Animal Instincts

| Michael Schubert

Meet the four-legged diagnosticians who are sniffing out cancer’s secrets

Inside the Lab Oncology

The Limitations of Cancer Tests

| Melissa Pessin, Elizabeth Wagar, Lakshmi Ramanathan

Interpreting routine laboratory tests in oncology applications can be challenging

Subspecialties Training and education

When Is a Cancer Not a Cancer?

| Michael Schubert

New diagnostic criteria for thyroid neoplasms prevents aggressive treatment of indolent tumors

Diagnostics Genetics and epigenetics

Biomarker to Predict Breast Cancer

| Michael Schubert

Ki67 in healthy breast tissue may indicate increased risk of developing the disease

Diagnostics Microscopy and imaging

Defining Boundaries

| Michael Schubert

Third harmonic generation microscopy could allow surgeons to spot and remove tumor tissue in real-time

Diagnostics Oncology

Research Timeline

An overview of epithelio-mesenchymal transition

Diagnostics Oncology

The PDAC Key

| Michael Schubert

Pancreatic cancer cells don’t seem to rely on EMT for metastasis – but it plays a key role in their ability to resist our best chemotherapy options

Diagnostics Oncology

Tracking the Transition

| Dingcheng Gao

A triple-transgenic mouse model allows researchers to trace the lineage of EMT tumor cells, and reveals the transition’s surprising lack of significance in metastasis

Diagnostics Oncology

Proceed With Caution

| Shyamala Maheswaran

Two recent studies on EMT may revise the field’s understanding of the process – but it’s important to keep in mind both the breakthroughs and the limitations of the work

Diagnostics Oncology

Cells on the (Invasion) Front Lines

| Michael Schubert

Long thought to be a key component of the metastatic process, researchers are now questioning long-held beliefs of the role of epithelial-to-mesenchymal transition

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