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Microbiology and immunology

Diagnostics Microbiology and immunology

Out With the Old

| Luke Turner

Existing tests for rapid diagnosis of TB are costly and insufficient – but second-generation assays with improved sensitivity could be the answer

Subspecialties Clinical care

An Inside Look at the CNS

| Danielle Fortuna, Mark Curtis

Neurological disorders can be invasive and time-consuming to diagnose, but profiling cytokines in the cerebrospinal fluid can lessen that burden

Diagnostics Clinical care

Act Fast Against Infection

| Matthieu Legrand

To confront the increasing problem of antimicrobial resistance in medicine, laboratorians and clinicians must pursue rapid diagnostics

Subspecialties Genetics and epigenetics

Putting a Bug in Your Ear

| Michael Schubert

Variants in the FUT2 gene may increase susceptibility to otitis media by altering the microbiome of the middle ear

Diagnostics Liquid biopsy

A Diagnostic to Drool Over?

| Luke Turner

The use of saliva as a diagnostic fluid seems an attractive option – especially now that research reveals circulating tumor DNA in the fluid

Subspecialties Microbiology and immunology

A Win-Win-Win Situation

| Bamidele Farinre

How consolidating molecular diagnostics has improved service delivery for the Great Ormond Street Hospital microbiology department

Subspecialties Microbiology and immunology

Monitoring the Microbiome

| Luke Turner

Differences in bacterial diversity in the gut could be used to identify patients with Barrett’s esophagus and esophageal cancer

Diagnostics Point of care testing

Smarter, Faster Sepsis Testing

| David Ludvigson

A two-stage model featuring point of care sepsis testing and follow-up lab results could improve treatment and reduce the risk of mortality

Outside the Lab Biochemistry and molecular biology

Pre-Empting Relapse

| Luke Turner

A new DNA test that can detect treatment-resistant mutations could prove crucial for patients with acute myeloid leukemia, providing an early indication that targeted therapeutic intervention is needed

Subspecialties Biochemistry and molecular biology

An Untrustworthy Myeloma Assay?

The serum free light chain assay for myeloma may miss as many as one in four cases of lambda chain-associated disease, so additional testing is advised

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