Out With the Old
Could second generation interferon-γ release assays replace existing tests and transform TB diagnosis through improved sensitivity?
Luke Turner | | Quick Read
Tuberculosis (TB) testing is big business: tens of thousands of patients that display suggestive symptoms are tested in the UK alone. In countries where TB incidence is relatively low, interferon-γ release assays (IGRAs) are commonly used for diagnosis – but new research has found that these blood tests cannot accurately rule out the disease. In addition, second-generation IGRAs showed much higher sensitivity than existing tests (1), potentially heralding their replacement.
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