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Hematology

Inside the Lab Technology and innovation

Photoacoustic Microscopy Makes All the Right Noises

| Luke Turner

A new laser technique uses vibrations to listen to the metabolic activity of cancer cells, shedding light (and sound) on intratumoral heterogeneity.

Subspecialties Microbiology and immunology

Spotting Sepsis Sooner

| Rachel Burnside

Sepsis kills millions and costs billions each year, but a new approach that analyzes morphological changes in monocytes could help

Diagnostics Hematology

Casting a Broader Net

| Luke Turner

Pancreatic cancer is associated with poor patient outcomes; could a new blood test improve screening accuracy for those at risk?

Diagnostics Analytical science

Unraveling the D-Amino Acid Mystery

| Luke Turner

D-serine has shown potential as a biomarker for the prediction of kidney function and the detection of chronic kidney disease

Diagnostics Microbiology and immunology

Out With the Old

| Luke Turner

Existing tests for rapid diagnosis of TB are costly and insufficient – but second-generation assays with improved sensitivity could be the answer

Diagnostics Hematology

Improving Our Early Warning System for AML

| Amanda Winters

The gold standard for monitoring acute myeloid leukemia relapse after bone marrow transplant is chimerism testing – but is it sensitive enough?

Inside the Lab Clinical care

Biochip Breakthrough

| Luke Turner, Arjang Hassibi

With antimicrobial resistance an ever-increasing threat to modern medicine, a new breakthrough may rapidly identify drug-resistant microbe strains to ensure effective treatment

Outside the Lab Biochemistry and molecular biology

Pre-Empting Relapse

| Luke Turner

A new DNA test that can detect treatment-resistant mutations could prove crucial for patients with acute myeloid leukemia, providing an early indication that targeted therapeutic intervention is needed

Outside the Lab Biochemistry and molecular biology

Fighting Resistance in Bloodstream Infections

| Luke Turner

When bacteria become resistant to the last line of defense, rapid detection and treatment is more important than ever. A new assay can help with treatment selection for carbapenem-resistant infections

Subspecialties Screening and monitoring

Enzymology: A Whistle-Stop Tour of GOSH Pathology

| Derek Burke

How do the labs at GOSH use enzyme assays to help their infant patients?

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