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Precision medicine

Outside the Lab Training and education

Stepping Out From Behind the Microscope

| Roisin McGuigan

Sitting Down With… Blair Holladay, CEO of the American Society of Clinical Pathology (ASCP), Chicago, Illinois, USA.

Diagnostics Digital and computational pathology

The Changing Face of Pathology

| Han van Krieken

Han van Krieken discusses the ways in which laboratory medicine is evolving, the difference between old and young pathologists, and the obstacles facing both of them today

Inside the Lab Genetics and epigenetics

(Not) All About That Base

| Michael Schubert

Genetic analysis isn’t the only tool for delivering personalized treatment; a novel technique for matching tumors with appropriate therapies could prove a rapid and reliable alternative

Inside the Lab Genetics and epigenetics

A Liquid Revolution?

| Roisin McGuigan

A review of the clinical uses of liquid biopsy show it’s poised to make a splash in pathology

Inside the Lab Genetics and epigenetics

Tumor Genotyping – How Accurate Are You?

| Joe Whittaker

In the era of personalized medicine, the use of reference materials is more important now than ever.

Diagnostics Genetics and epigenetics

A Personalized Reality

| Matthew Smith , George Burghel

Next generation sequencing holds much promise for personalized cancer diagnosis, treatment and management, but how is this being realized and what does the future hold?

Inside the Lab Oncology

Tumor Only Sequencing Could Be Misleading

| Michael Schubert

Many hospitals sequence patients’ tumor genomes to personalize their treatment – but without sequencing normal tissue, this can harm rather than heal.

Inside the Lab Genetics and epigenetics

The 100,000 Genomes Project

| Stephanie Vine

Ambitious UK sequencing project aims to learn more about patients with cancer and rare diseases

Outside the Lab Oncology

The Undisputable Value of Pharmacogenetic Testing

| Ron H. N. van Schaik

Pharmacogenetic testing is escalating in both the number of requests and its importance – these are undisputable facts.

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