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Precision medicine

Outside the Lab Profession

Perfecting the Translational Balancing Act

Sitting Down With… Jennifer Grandis, Professor, Department of Otolaryngology – Head and Neck Surgery, Associate Vice Chancellor – Clinical and Translational Research, University of California, San Francisco, USA.

Subspecialties Genetics and epigenetics

Disrupting Cytogenetics in the Clinic

| George Vasmatzis

To select the right treatment for each cancer patient, we need fast, accurate and cost effective ways to characterize tumors. Now, with newly developed algorithms and protocols, mate pair sequencing could well be the tool we’ve been seeking

Inside the Lab Profession

Empowering Pathologists

| Ralf Huss

Digital pathology and tissue image analysis tools are essential to developing companion diagnostics and enabling pathologists to support clinical decisions, but there is still work to be done…

Subspecialties Genetics and epigenetics

Single-Gene Source for Schizophrenia?

| Michael Schubert

Mutations in the SETD1A gene are rare, but significantly increase patients’ risk of schizophrenia and neurodevelopmental disorders

Inside the Lab Genetics and epigenetics

An On/Off Switch for Heart Attacks

| Michael Schubert

ANGPTL4 mutations can reduce patients’ risk of heart attack by up to 50 percent – so could neutralizing the gene offer a new route to prevention?

Inside the Lab Screening and monitoring

A PSA on PSA

| Michael Schubert

The cost of prostate cancer screening can outweigh its benefits – but the right strategy can maximize the return on investment

Inside the Lab Screening and monitoring

Small Mutations, Big Impact

| Michael Schubert

A new study reveals that screening for mutations in patients with advanced lung cancer can focus their treatment options and improve success rates

Inside the Lab Biochemistry and molecular biology

A Question of Value

| Fedra Pavlou

Molecular testing is changing the face of healthcare. But how far should it go?

Subspecialties Precision medicine

Field of Genes

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The Penn State Hershey Institute for Personalized Medicine benefits from a unique “build it as you need it” growth pattern

Outside the Lab Precision medicine

Young But Powerful

| David Roth

Penn Medicine’s Center for Personalized Diagnostics is on a mission to improve patient care using the power of genomics

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