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Precision medicine

Inside the Lab Genetics and epigenetics

Load Versus Response

| Jonathan James

Higher tumor mutational burden is linked to improved survival across multiple cancer types.

Diagnostics Precision medicine

Time, Money, and Tissue

| Jason Ramos

Simultaneous multiplex immunohistochemistry can provide efficient testing of multiple targets when diagnosing and selecting treatment for cancer

Diagnostics Companion diagnostics

Improving Patient Outcomes

| Eslie Dennis, Eric Walk, Ken Bloom, Mark Kockx

A response to David Rimm’s letter that supports the role of PD-L1 testing in improving outcomes for cancer patients.

Diagnostics Companion diagnostics

Welcome to Our Kitchen

| David L. Rimm

David Rimm challenges the sensitivity and reproducibility of a new assay for PD-L1 detection.

Diagnostics Liquid biopsy

Fine-Tuning Immunotherapy

| George Karlin-Neumann

Techniques like droplet digital PCR technology can assist with early monitoring of cancer immunotherapy to ensure the right treatment for each patient

Outside the Lab Profession

The Spice of Life

| Luke Turner

Genomic research has a diversity problem that could restrict the future effectiveness of precision medicine for minority groups

Inside the Lab Precision medicine

PREDICTive Power

| Jonathan James

Prostate cancer prognosis presents a challenge – but a new algorithmic tool may help personalize predictions

Diagnostics Omics

Serving China’s Breast Cancer Community

| Franklin Libenson

Decentralized genomic testing in China will allow earlier breast cancer diagnosis and more personalized treatment decisions

Diagnostics Genetics and epigenetics

The Right Dose for the Right Person

| Michael Schubert

New guidelines for CYPC29 genotyping ensure that the correct alleles are tested and patients are prescribed the correct doses of common drugs

Inside the Lab Digital and computational pathology

Long Live the (Digital) Revolution!

| Dariusz Borys

Pathology’s great strides forward in artificial intelligence and machine learning will bring us to the forefront of personalized medicine

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