Welcome to our annual celebration of the great and inspirational minds that underpin the medical laboratory. For 2021, we present some of the most inspirational pathologists and laboratory medicine professionals in six different categories...
The gold standard for monitoring acute myeloid leukemia relapse after bone marrow transplant is chimerism testing – but is it sensitive enough?
Liquid biopsy has shown promise as a rapid, minimally invasive way to profile tumors – but are commercially available tests accurate and consistent?
The use of saliva as a diagnostic fluid seems an attractive option – especially now that research reveals circulating tumor DNA in the fluid
Lisa M. Wright
To harness liquid biopsy’s many advantages, it’s vital to ensure appropriate testing – and cfDNA synthetic plasma reference standards can help
Niamh Buckley, Laura Feeney, James Beirne, and Paul Mullan
Markers such as DNA methylation, analyzed by liquid biopsy, may improve on ovarian cancer testing options like gold standard CA125
New biomarker sensing technology can detect miniscule concentrations of molecules in the blood to assist with patient monitoring
Epigenetics may combine with liquid biopsy to offer an effective way of detecting early-stage cancers and recurrences
Alexander Dobrovic and Cloud Paweletz
When seeking the greatest benefit from liquid biopsy, droplet digital PCR can help by offering speed, sensitivity, and absolute quantitation
A combination of magnetic particles that bind circulating tumor cells and a magnetic wire that samples them directly from the vein could lead to earlier diagnosis
When bacteria become resistant to the last line of defense, rapid detection and treatment is more important than ever. A new assay can help with treatment selection for carbapenem-resistant infections
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Epigenetics of Early Arrivals
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A Century of Excellence