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Biochemistry and molecular biology

Diagnostics Biochemistry and molecular biology

Go with the Flow

| Mike Keeney, Jeannine Holden

Flow cytometric immunophenotyping can speed up and standardize the diagnosis of leukemia and non-Hodgkin lymphoma

Inside the Lab Technology and innovation

HIER, Further, Faster

| Jason Ramos, Spontaneous Russell

Automated IHC staining has limited capacity for heat-induced epitope retrieval – but a move to hybrid power lifts that barrier.

Inside the Lab Technology and innovation

Photoacoustic Microscopy Makes All the Right Noises

| Luke Turner

A new laser technique uses vibrations to listen to the metabolic activity of cancer cells, shedding light (and sound) on intratumoral heterogeneity.

Diagnostics Biochemistry and molecular biology

A Disease With Many Faces

| David R. Hout

Triple-negative breast cancer is not a single entity, and understanding each patient’s molecular subtype can influence treatment and outcomes

Diagnostics Hematology

Casting a Broader Net

| Luke Turner

Pancreatic cancer is associated with poor patient outcomes; could a new blood test improve screening accuracy for those at risk?

Diagnostics Analytical science

Unraveling the D-Amino Acid Mystery

| Luke Turner

D-serine has shown potential as a biomarker for the prediction of kidney function and the detection of chronic kidney disease

Diagnostics Analytical science

Biomarkers Beyond Our Wildest Dreams

| Luke Turner

Different glycosylation patterns in patients with idiopathic REM sleep behavior disorder could predict the future onset of neurodegenerative disease

Subspecialties Biochemistry and molecular biology

Jagged Little Pill (for Cancer)

| Luke Turner

A Jagged protein directly linked to cancer metastasis could be targeted to assess the aggressiveness of tumors and prevent their rapid spread

Inside the Lab Biochemistry and molecular biology

A Fluid Future

| Luke Turner

Liquid biopsy has shown promise as a rapid, minimally invasive way to profile tumors – but are commercially available tests accurate and consistent?

Diagnostics Biochemistry and molecular biology

Treat or Surveil

| George Vasmatzis and John Cheville

Newly discovered genetic alterations could indicate whether treatment or active surveillance is the best option for low-risk prostate cancer patients

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