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Outside the Lab Technology and innovation

Pilsen’s Second-Biggest Export: Pathology

| Ivan Damjanov

From plastic beer case furniture to the largest pathology laboratory in Eastern Europe

Diagnostics Histology

Listen to your Gut

| Jianchao Li, Scott Crawley

Recent studies reveal that the organizational protein complexes in gut microvilli closely resemble those of ear stereocilia – so what does this mean for genetic disorders of either?

Inside the Lab Microbiology and immunology

A Kryptonite for Pathogens

| Timothy Wencewicz

Could antibiotics that target virulence factors be the key to defeating multi-drug resistant “bugs of steel?”

Subspecialties Technology and innovation

The Core of the Problem

| Inti Zlobec

Next generation tissue microarrays overcome punching inaccuracies and bring the technique into the era of precision medicine

Diagnostics Oncology

Proceed With Caution

| Shyamala Maheswaran

Two recent studies on EMT may revise the field’s understanding of the process – but it’s important to keep in mind both the breakthroughs and the limitations of the work

Diagnostics Oncology

Cells on the (Invasion) Front Lines

| Michael Schubert

Long thought to be a key component of the metastatic process, researchers are now questioning long-held beliefs of the role of epithelial-to-mesenchymal transition

Subspecialties Histology

Undervalued and Underused

| Susan Rollins

Ultrasound guided fine needle aspiration biopsy cytology streamlines and improves cancer diagnosis

Outside the Lab Technology and innovation

On the Spot Diagnosis

| Laura Lechuga

Mobile devices promise a new future of point-of-care diagnostics for all

Inside the Lab Profession

Empowering Pathologists

| Ralf Huss

Digital pathology and tissue image analysis tools are essential to developing companion diagnostics and enabling pathologists to support clinical decisions, but there is still work to be done…

Subspecialties Genetics and epigenetics

Single-Gene Source for Schizophrenia?

| Michael Schubert

Mutations in the SETD1A gene are rare, but significantly increase patients’ risk of schizophrenia and neurodevelopmental disorders

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