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Screening and monitoring

Subspecialties Microbiology and immunology

Monitoring the Microbiome

| Luke Turner

Differences in bacterial diversity in the gut could be used to identify patients with Barrett’s esophagus and esophageal cancer

Outside the Lab Screening and monitoring

Steps Forward in Cancer Screening

| Luke Turner

We round up the latest news in pathology and laboratory medicine with these bite-sized stories

Diagnostics Analytical science

An Analytical Pill

| Michael Schubert

An electronic gas-sensing capsule may increase diagnostic and monitoring accuracy in disorders of the digestive tract

Diagnostics Genetics and epigenetics

The Evolution of Epigenetic Biomarkers

| Niamh Buckley, Laura Feeney, James Beirne, and Paul Mullan

Markers such as DNA methylation, analyzed by liquid biopsy, may improve on ovarian cancer testing options like gold standard CA125

Diagnostics Analytical science

Sensing the Tiniest Change

| Menno Prins

New biomarker sensing technology can detect miniscule concentrations of molecules in the blood to assist with patient monitoring

Diagnostics Genetics and epigenetics

Thinking Outside the (Genome) Box

| Jason Mellad

Epigenetics may combine with liquid biopsy to offer an effective way of detecting early-stage cancers and recurrences

Inside the Lab Clinical care

Biochip Breakthrough

| Luke Turner, Arjang Hassibi

With antimicrobial resistance an ever-increasing threat to modern medicine, a new breakthrough may rapidly identify drug-resistant microbe strains to ensure effective treatment

Outside the Lab Biochemistry and molecular biology

Pre-Empting Relapse

| Luke Turner

A new DNA test that can detect treatment-resistant mutations could prove crucial for patients with acute myeloid leukemia, providing an early indication that targeted therapeutic intervention is needed

Inside the Lab Clinical care

Gone Fishing

A combination of magnetic particles that bind circulating tumor cells and a magnetic wire that samples them directly from the vein could lead to earlier diagnosis

Subspecialties Biochemistry and molecular biology

An Untrustworthy Myeloma Assay?

The serum free light chain assay for myeloma may miss as many as one in four cases of lambda chain-associated disease, so additional testing is advised

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