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SureSeq™ FFPE DNA Repair Mix* and hybridisation-based enrichment provide superior variant detection in next-generation sequencing even from 10 ng of severely formalin compromised DNA

Introduction

With advances in next-generation sequencing (NGS) technology, genetic information can be extracted from an increasingly diverse range of samples. Formalin-fixed, paraffin-embedded (FFPE) storage is a standard method for archiving tissue biopsies and these biopsies can be used in NGS, for example to study cancer development and progression.

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