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Diagnostics

Diagnostics Profession

Science Searches Simplified

| Elizabeth Iorns

Researcher and entrepreneur explains how she hopes to help others take a great scientific idea to reality

Diagnostics Clinical care

Waging War on Pathogens

| Nancy Hanson

Molecular diagnostics are welcome reinforcements in the raging battle against institutional infection and antibiotic resistance

Diagnostics Genetics and epigenetics

Biomarker to Predict Breast Cancer

| Michael Schubert

Ki67 in healthy breast tissue may indicate increased risk of developing the disease

Diagnostics Microscopy and imaging

Defining Boundaries

| Michael Schubert

Third harmonic generation microscopy could allow surgeons to spot and remove tumor tissue in real-time

Diagnostics Oncology

Research Timeline

An overview of epithelio-mesenchymal transition

Diagnostics Oncology

The PDAC Key

| Michael Schubert

Pancreatic cancer cells don’t seem to rely on EMT for metastasis – but it plays a key role in their ability to resist our best chemotherapy options

Diagnostics Oncology

Tracking the Transition

| Dingcheng Gao

A triple-transgenic mouse model allows researchers to trace the lineage of EMT tumor cells, and reveals the transition’s surprising lack of significance in metastasis

Diagnostics Microscopy and imaging

Image of the Month

The variability in color and texture of these solid crystalline deposits arises from differences in the stones’ primary compounds.

Diagnostics Histology

Listen to your Gut

| Jianchao Li, Scott Crawley

Recent studies reveal that the organizational protein complexes in gut microvilli closely resemble those of ear stereocilia – so what does this mean for genetic disorders of either?

Diagnostics Oncology

Proceed With Caution

| Shyamala Maheswaran

Two recent studies on EMT may revise the field’s understanding of the process – but it’s important to keep in mind both the breakthroughs and the limitations of the work

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