One TINY Step at a Time
How to diagnose Kaposi’s sarcoma in areas without reliable infrastructure
Michael Schubert | | Quick Read
Kaposi’s sarcoma (KS) presents a diagnostic challenge even in optimal healthcare settings. This is because presentation can be extremely heterogeneous, and there are many clinical entities which mimic KS morphologically. Accurate diagnosis, which conventionally requires experienced dermatopathologists, is critical to avoid unwarranted chemotherapy – and to ensure correct therapy for mimicking conditions. But histopathologic diagnosis is not always possible in resource-limited settings, such as sub-Saharan Africa, where KS is one of the most common cancers among adults. In these settings, clinicians must often diagnose KS only via macroscopic observation and, unfortunately, this is often incorrect. Even where pathology is available, lengthy turnaround times in interpretation often render the findings useless.
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