Genetics and epigenetics

New software can reconstruct T cell receptor sequences from RNA sequencing data

A new study reveals that screening for mutations in patients with advanced lung cancer can focus their treatment options and improve success rates

A blood test for circulating tumor DNA can reveal what’s going on below the surface of malignant melanoma

Molecular testing is changing the face of healthcare. But how far should it go?

The Penn State Hershey Institute for Personalized Medicine benefits from a unique “build it as you need it” growth pattern

Penn Medicine’s Center for Personalized Diagnostics is on a mission to improve patient care using the power of genomics

How is fierce ambition translated into the reality of building two world-class personalized healthcare institutes?

Newborn screening programs that seek out common mutations often fail to diagnose cystic fibrosis in nonwhite populations.

Shotgun sequencing is a powerful tool in microbial genomics, but viral genomes have proven tough to crack.

Hirschsprung disease (HSCR) is a congenital form of megacolon that occurs when the ganglion cells of the digestive tract fail to develop, impairing or eliminating function.