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The Pathologist / Issues / 2026 / September / Urine Bladder Cancer Test Could Triage Cystoscopy
Oncology Liquid biopsy Screening and monitoring Research and Innovations Molecular Pathology

Urine Bladder Cancer Test Could Triage Cystoscopy

Real-world UK study suggests molecular testing could help prioritize patients with hematuria for urgent bladder investigation

09/11/2026 News 2 min read
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5 Key Takeaways
  • 1

    A urine-based DNA test can identify patients with hematuria who need urgent cystoscopy, allowing lower-risk patients to delay the procedure.

  • 2

    The GALEAS Bladder assay detected 71 of 77 bladder cancers and had a negative predictive value exceeding 99 percent.

  • 3

    The study involved 964 participants, with 77 confirmed cases of bladder cancer, highlighting the assay's diagnostic capabilities.

  • 4

    Using the urine test could reduce immediate cystoscopies by 730 per 1000 patients without compromising overall clinical benefit.

  • 5

    The study indicates a potential role for molecular testing as a triage tool, but randomized evidence is needed for broader recommendations.

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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