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The Pathologist / Issues / 2026 / September / Fallowed Fields Tied to Valley Fever
Infectious Disease Screening and monitoring Research and Innovations

Fallowed Fields Tied to Valley Fever

California surveillance data reveal associations between land use and coccidioidomycosis incidence

09/09/2026 News 3 min read
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Fallowed Fields Tied to Valley Fever

Overview

A population-based study in California found associations between land use and coccidioidomycosis incidence. Newly fallowed farmland and specific agricultural practices were linked to higher rates of Valley fever.

Background

Coccidioidomycosis, or Valley fever, is an infectious disease caused by inhaling spores of Coccidioides fungi. Understanding the environmental factors influencing its incidence is crucial, especially as cases have risen significantly in recent years.

Data Highlights

YearReported Cases
20081,708
20179,778

Key Findings

  • Incidence of coccidioidomycosis increased from 1,708 cases in 2008 to 9,778 in 2017.
  • Higher incidence was associated with larger areas of shrubland, barren ground, and grassland.
  • Newly fallowed land and land fallowed in the previous 4 years were linked to higher incidence.
  • Specific crops, such as grain and hay, were associated with higher incidence, while deciduous fruit and nut orchards were linked to lower incidence.
  • The study did not confirm the presence of Coccidioides in agricultural soils or dust.

Clinical Implications

The findings suggest that environmental and agricultural factors may influence the risk of coccidioidomycosis. Clinicians should consider these factors when evaluating patients with respiratory symptoms in endemic areas.

Conclusion

This study highlights the relationship between land use and coccidioidomycosis incidence, emphasizing the need for further research into environmental determinants of this disease.

Related Resources & Content

  1. American Journal of Epidemiology, 2023 -- Assessing the Endemicity of Coccidioidomycosis by Incorporating Imperfect Detection through Spatio-Temporal Occupancy Modeling
  2. International Journal of Infectious Diseases, 2026 -- Establishing thresholds for azole tolerance and persistence in Aspergillus fumigatus to study their impact on voriconazole treatment in vivo
  3. The Journal of Infectious Diseases, 2023 -- Leveraging Canine Serological Data to Enhance Insights into Coccidioidomycosis: A One Health Perspective
  4. Ophthalmology Management, 2021 -- Fields mark the spot
  5. Comparison of oral fluconazole and itraconazole for progressive, nonmeningeal coccidioidomycosis. A randomized, double-blind trial. Mycoses Study Group - PubMed, 2000
  6. IDSA Practice Guidelines
  7. Comparison of oral fluconazole and itraconazole for progressive, nonmeningeal coccidioidomycosis. A randomized, double-blind trial. Mycoses Study Group - PubMed
  8. Accuracy of Plasma Cell-Free DNA PCR for Diagnosis of Coccidioidomycosis - PubMed

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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