Objective:

To investigate the influence of color vision deficiency (CVD) on the detection and survival outcomes of bladder and colorectal cancers, highlighting its potential implications for patient care.

Key Findings:

• Patients with bladder cancer and CVD showed lower overall survival compared to controls (p-value needed).
• A 20-year analysis indicated higher mortality in bladder cancer patients with CVD (p-value needed).
• No significant survival difference was found in colorectal cancer patients with and without CVD.

Interpretation:

Impaired recognition of visible blood in urine may lead to delayed presentation and poorer outcomes in bladder cancer for individuals with CVD, as they may misinterpret or overlook these critical symptoms.

Limitations:

• Reliance on diagnostic coding within electronic health records may introduce biases.
• Limited availability of staging data restricts assessment of disease severity at presentation.

Conclusion:

The study highlights a potential diagnostic gap related to visual impairment affecting detection pathways in bladder cancer, emphasizing the need for awareness and assessment of CVD in clinical practice, with less impact observed in colorectal cancer.