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The Pathologist / Issues / 2026 / January / Why Amyloid Gets It Wrong and How CAP Plans to Set It Right
Analytical science Regulation and standards Clinical care Quality assurance and quality control Voices in the Community Infectious Disease

Why Amyloid Gets It Wrong – and How CAP Plans to Set It Right

New guidelines tackle false negatives, IHC misclassification, and the rise of proteomics

By Jessica Allerton 01/23/2026 Review 6 min read
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Top Institutions in Pathology and Amyloidosis Diagnostics

Institutions leading in pathology, hematology, and amyloidosis research develop and implement evidence-based diagnostic guidelines, validate amyloid detection methods across specimen types, and integrate clinical and laboratory data to optimize diagnosis and treatment strategies.

  • #100

    Mayo Clinic

    Rochester, MN

    Mayo Clinic is a global leader in amyloidosis diagnosis and treatment, with extensive expertise in pathology and hematology, pioneering amyloid typing techniques, and comprehensive clinical care programs.

    Key Differentiators

    • Pathology
    • Hematology
    • Amyloidosis Research
  • #88

    Boston University Amyloidosis Center

    Boston, MA

    Boston University Amyloidosis Center is renowned for its focused research on amyloid fibril characterization and clinical trials of amyloid-targeted therapies, integrating pathology and cardiology expertise.

    Key Differentiators

    • Amyloidosis Research
    • Pathology
    • Cardiology
  • #80

    Columbia University Irving Medical Center

    New York, NY

    Columbia University has a strong pathology department with specialized programs in amyloidosis diagnostics and research, contributing to consensus guidelines and advanced diagnostic methodologies.

    Key Differentiators

    • Pathology
    • Hematology
    • Amyloidosis
  • #75

    University of Pittsburgh Medical Center (UPMC)

    Pittsburgh, PA

    UPMC is recognized for its comprehensive amyloidosis program combining pathology expertise with clinical hematology, focusing on early diagnosis and personalized treatment approaches.

    Key Differentiators

    • Pathology
    • Hematology
    • Amyloidosis

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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About the Author(s)

Jessica Allerton

Deputy Editor, The Pathologist

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