5 Key Takeaways

• 1

  Newborns of mothers with multiple chronic conditions face increased risks of severe neonatal morbidity and mortality.

• 2

  The study analyzed over 1 million births, revealing a dose-response relationship between maternal conditions and neonatal outcomes.

• 3

  Newborns of mothers with three or more chronic conditions had nearly double the risk of severe neonatal morbidity.

• 4

  Cardiometabolic conditions significantly elevate the risk of adverse neonatal outcomes, especially when severe.

• 5

  Integrating maternal chronic disease history into prenatal assessments can improve neonatal risk stratification.