Subspecialties Oncology, Omics

Addressing the incomplete mutational landscape in pediatric cancers with Optical Genome Mapping

10/30/2023

sponsored by Bionano

October 30, 2023 - 11am ET

In this Bionano in Motion webinar, we explore the utility and validity of an innovative strategy, proposed by Dr Brandes from Heinrich-Heine University and University Hospital Dusseldorf that combines Optical Genome Mapping (OGM) and whole exome sequencing (WES) in 60 HD and ETV6::RUNX1+ BCP-ALL cases. This study shows that OGM detected a high number of additional SVs not identified using the conventional methods, including (subclonal) IKZF1 deletions, a prognostically relevant subtype.

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