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Subspecialties Neurology, Liquid biopsy, Oncology, Genetics and epigenetics

Predicting Prognosis in Glioblastoma

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults – and the deadliest. Only five to 10 percent of patients survive longer than five years. Predicting prognosis can be particularly difficult because surgical procedures are complicated and invasive, a challenge exacerbated by the tumor’s heterogeneity. But now, a team from the Abramson Cancer Center of the University of Pennsylvania have found that patients with a higher concentration of circulating free DNA (cfDNA) have shorter progression-free survival. Senior author Erica Carpenter believes this underlines the potential utility of liquid biopsy for monitoring brain tumors.

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About the Author

Luke Turner

While completing my undergraduate degree in Biology, I soon discovered that my passion and strength was for writing about science rather than working in the lab. My master’s degree in Science Communication allowed me to develop my science writing skills and I was lucky enough to come to Texere Publishing straight from University. Here I am given the opportunity to write about cutting edge research and engage with leading scientists, while also being part of a fantastic team!

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