Predicting Prognosis in Glioblastoma
The link between cfDNA concentration and progression-free survival for GBM patients
Luke Turner | | Quick Read
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults – and the deadliest. Only five to 10 percent of patients survive longer than five years. Predicting prognosis can be particularly difficult because surgical procedures are complicated and invasive, a challenge exacerbated by the tumor’s heterogeneity. But now, a team from the Abramson Cancer Center of the University of Pennsylvania have found that patients with a higher concentration of circulating free DNA (cfDNA) have shorter progression-free survival. Senior author Erica Carpenter believes this underlines the potential utility of liquid biopsy for monitoring brain tumors.
Read the full article now
Log in or register to read this article in full and gain access to The Pathologist’s entire content archive. It’s FREE!
Or register now - it’s free!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Pathologist magazine