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Subspecialties Oncology, Microscopy and imaging

Case of the Month

Case history


An 80-year-old male presented with weight loss. Physical examination detected an enlarged liver. Abdominal CT/MRI revealed: a 9 x 6.5 cm lesion in segment VIII of the right liver lobe, with central necrosis. Additionally, lesions were found in segments III and IVb measuring 3 cm and 4 cm, respectively. Lower pole of the right kidney showed a 1.4 cm lesion and multiple nodular lesions were seen in both lungs. Biopsy of the liver lesion is shown.

Open the digital slide here

H&E

IHC HepPar1

IHC Glypican3

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Submitted by Fred Bosman and Grishma Shresta, Patan Academy of Health Sciences, Patan, Nepal

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About the Authors
Fred Bosman

Fred Bosman is Professor Emeritus at the University Institute of Pathology, University Medical Center of Lausanne, Switzerland.


Grishma Shresta

Patan Academy of Health Sciences, Patan, Nepal

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