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ChipCytometry™ is a powerful tool for spatially resolved multiplexing that enables the quantitative measurement of dozens of protein biomarkers on a single cell or tissue sample. High-resolution, high dynamic range imaging enables quantitative single cell analysis of high- and low-expressing proteins, while maintaining critical information about cell morphology and tissue architecture.
Samples are loaded onto ZellSafe™ chips to preserve sample integrity during serial delivery of reagents. A cocktail of up to 5 fluorescently conjugated antibodies is delivered in successive rounds of staining, imaging, and photobleaching. A proprietary algorithm is used to generate an image overlay for cell segmentation and quantification of cellular phenotypes.
