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RNAscope^® Technology is a cutting-edge multiplex nucleic acid in situ hybridization technology which enables simultaneous signal amplification and background noise suppression resulting in single-RNA-molecule detection even in partially degraded samples. Rigorous double Z probes design eliminates cross hybridization to unintended targets and routinely distinguishes RNA sequences with up to 85% homology. Unique to this technology, RNAscope^® delivers quantitative, sensitive and specific molecular detection of RNA species on a cell-by-cell basis with morphological context in a single assay. This enables researchers to visualize which genes are expressed, localize where they are expressed, and quantify the level of expression.Advanced Cell Diagnostics, Inc. (ACD) is a leader in the field of molecular pathology, developing cell and tissue‐based diagnostic tests for personalized medicine. The company’s products and services are based on its proprietary RNAscope^® technology, the first automated multiplex chromogenic and fluorescent in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single‐molecule sensitivity. RNAscope^® assays are currently used by thousands of customers, including all of the global top 10 pharmaceutical companies, world leading academic institutions and many cutting edge biotechnology companies to validate biomarkers for the management of cancer and other diseases.

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Contact Information:

Advanced Cell Diagnostics, S.r.l.
Via Calabria15
20090 Segrate (Milano) – Italy
Phone: +39.02.95360323
Fax: +39.02.95360992
Email: info@acdbio.com

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