Woo Cheal Cho
Assistant Professor, The University of Texas MD Anderson Cancer Center, Texas, USA
Exciting developments and trends? One of the most thrilling advancements, particularly in dermatopathology, is the integration of advanced molecular testing into routine practice. This evolution enables the identification of potentially targetable genetic abnormalities, accurate diagnosis of complex lesions, and even the discovery of novel tumor types based on specific molecular alterations such as gene fusions. This transformation not only enhances diagnostic precision but also opens up new avenues for personalized treatment strategies – ultimately improving patient outcomes.
Missing from the diagnostic toolbox? Despite the advancements in emerging immunohistochemical and molecular studies, what we need in our diagnostic toolbox is sharpened attention to detail. In my subspecialty of dermatopathology, many significant diagnostic discrepancies I've observed over the years stem from inadequate histopathologic evaluation or misinterpretation of presented data (i.e., histopathologic features). I’ve heard someone saying, “high-power (high-magnification examination) equals low IQ.” However, histopathologic diagnosis isn't a race; accuracy is paramount for patient care. I firmly believe that thorough evaluation – what I call "high-power" – translates directly into optimal patient outcomes.
Book recommendation? “The Three-Body Problem” is a book that all scientists should read. Not just because of its exploration into the potential existence of aliens (which I am a firm believer in the existence of, as it only makes sense statistically), but also because it raises profound questions about how scientific discovery and technological advancements impact humanity, ethics, and the universe. This novel encourages readers to critically examine the consequences of scientific pursuits and innovations, making it a thought-provoking and essential read for anyone who loves science.
